Table 2.
SNPs with Strongest Evidence of Association with C-Reactive Protein in the PARC Combined Stage 1 and Stage 2 Genome-Wide Association Study
| rs Number | Chr. | Position | Gene | Number with Nonmissing Genotype and CRP Phenotype | Log10 Bayes Factor | p Value(Permutation) |
|---|---|---|---|---|---|---|
| rs2794520 | 1 | 157945440 | CRP | 1682 | 6.6 | < 1 × 10−7 |
| rs2075650 | 19 | 50087459 | APOE | 1678 | 5.7 | < 1 × 10−7 |
| rs2592887 | 1 | 157919563 | CRP | 1680 | 4.8 | < 1 × 10−7 |
| rs6481464 | 10 | 60790490 | FAM13C1 | 1682 | 3.9 | 2 × 10−6 |
| rs7953249 | 12 | 119888107 | HNF1A | 1681 | 3.5 | 4 × 10−6 |
| rs735396 | 12 | 119923227 | HNF1A | 1682 | 3.3 | 5 × 10−6 |
| rs12093699 | 1 | 157914612 | CRP | 1682 | 3.3 | 7 × 10−6 |
| rs11265260 | 1 | 157966663 | CRP | 1682 | 3.3 | 7 × 10−6 |
| rs7730843 | 5 | 36578069 | SLC1A3 | 1679 | 3.2 | 1.5 × 10−5 |