Table 6.

Bayesian Imputation-Based Association Analysis of HNF1A SNPs and Log(CRP) Concentration: Results from PARC, CHS, and Both Studies Combined

				PARC		CHS		CHS + PARC Combined
rs #	Chr. 12 coordinate	Location	SNP Typed in PARC or CHS	Single-SNP BF Log(10)	p Value	Single-SNP BF Log(10)	p Value	Single-SNP BF Log(10)	p Value
rs7979473	119904643	Intron 1		+4.1	< 1 × 10−6	+11.1	< 1 × 10−6	+16.2	< 1 × 10−6
rs7979478	119904646	Intron 1		+4.1	< 1 × 10−6	+11.1	< 1 × 10−6	+16.2	< 1 × 10−6
rs2393791	119908339	Intron 1		+4.1	< 1 × 10−6	+11.0	< 1 × 10−6	+16.1	< 1 × 10−6
rs7310409	119909244	Intron 1		+4.1	< 1 × 10−6	+11.0	< 1 × 10−6	+16.1	< 1 × 10−6
rs2393775	119908957	Intron 1		+4.0	< 1 × 10−6	+11.0	< 1 × 10−6	+16.0	< 1 × 10−6
rs10774579	119889593	5′ flank		+4.4	< 1 × 10−6	+7.8	< 1 × 10−6	+14.7	< 1 × 10−6
rs7305618	119887315	5′ flank		+3.2	< 1 × 10−6	+6.4	< 1 × 10−6	+14.0	< 1 × 10−6
rs7953249	119888107	5′ flank	PARC	+3.6	< 1 × 10−6	+9.3	< 1 × 10−6	+13.7	< 1 × 10−6
rs2464195	119919858	Intron 7		+3.3	< 1 × 10−6	+8.6	< 1 × 10−6	+13.3	< 1 × 10−6
rs1169306	119922694	Intron 9		+3.1	< 1 × 10−6	+8.3	< 1 × 10−6	+13.2	< 1 × 10−6
rs2259816	119919970	Intron 7		+3.3	< 1 × 10−6	+8.6	< 1 × 10−6	+13.0	< 1 × 10−6
rs1169312	119925844	3′ UTR		+3.5	< 1 × 10−6	+8.5	< 1 × 10−6	+13.0	< 1 × 10−6
rs1169310	119923816	3′ UTR	CHS	+3.3	< 1 × 10−6	+8.6	< 1 × 10−6	+12.9	< 1 × 10−6
rs735396	119923227	Intron 9	PARC	+3.3	< 1 × 10−6	+8.5	< 1 × 10−6	+12.8	< 1 × 10−6
rs1169313	119927053	3′ flank		+3.4	< 1 × 10−6	+8.3	< 1 × 10−6	+12.7	< 1 × 10−6
rs1182933	119939005	3′ flank		+3.2	< 1 × 10−6	+7.5	< 1 × 10−6	+11.5	< 1 × 10−6
rs11065385	119907769	Intron 1		+3.5	< 1 × 10−6	+7.4	< 1 × 10−6	+11.5	< 1 × 10−6
rs1183910	119905190	Intron 1		+3.5	< 1 × 10−6	+7.5	< 1 × 10−6	+11.5	< 1 × 10−6
rs2649999	119864927	5′ flank		+2.8	< 1 × 10−6	+6.5	< 1 × 10−6	+11.3	< 1 × 10−6
rs2244608	119901371	Intron 1		+3.2	< 1 × 10−6	+6.8	< 1 × 10−6	+10.9	< 1 × 10−6
Global test	–	–		+2.9	2 × 10−5	+9.4	< 1 × 10−6	+14.5	< 1 × 10−6