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. 2008 Jun 15;22(12):1662–1676. doi: 10.1101/gad.1656808

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Copyright © 2008, Cold Spring Harbor Laboratory Press

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Figure 1. — Complete penetrance short Latency OS development. (A) Model of osteoblast differentiation and the putative stage of Osx-Cre expression. A and Figure 5D are composite diagrams based on the work of Aubin (2001), Franz-Odendaal et al. (2006), and Rodda and McMahon (2006). (B) Kaplan-Meier survival plots for the indicated genotypes: Osx-Cre⁺p53^+/+pRb^fl/fl, n = 49; Osx-Cre⁺ p53^fl/flpRb^+/+, n = 5; Osx-Cre⁺p53^fl/+pRb^fl/+, n = 30; Osx-Cre⁺p53^fl/+pRb^fl/fl, n = 9; Osx-Cre⁺p53^fl/flpRb^fl/+, n = 17; Osx-Cre⁺p53^fl/fl pRb^fl/fl, n = 12. (C) Representative presentation of OS of the lower jaw and femur, respectively.

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