TABLE 3.
Medication and procedure use* in cases and controls.
| Medication/ Procedure | IC Cases (n=239) | Controls (n=717) | p-value |
|---|---|---|---|
| IC Medications | |||
| Mean Yearly Cost | $1224 | $0 | <.0001 |
| Mean No. Users per year | 43 (18%) | 0 (0%) | <0.00001 |
| Number of unique users | 99 | 0 | |
| Mean number of fills per user | 9.5 | -- | |
| Oral Urinary Analgesics | |||
| Mean Yearly Cost | $24 | $0.62 | <.0001 |
| Mean No. Users per year | 40 (17%) | 10 (1%) | <0.00001 |
| Number of unique users | 115 | 43 | |
| Mean number of fills per user | 4.4 | 1.4 | .001 |
| Oral Antibiotics | |||
| Mean Yearly Cost | $228 | $67 | <.0001 |
| Mean No. Users per year | 98 (41%) | 155 (22%) | <0.00001 |
| Number of unique users | 199 | 421 | |
| Mean number of fills per user | 6.2 | 3.4 | <.0001 |
| Oral Narcotics | |||
| Mean Yearly Cost | $351 | $97 | .0006 |
| Mean No. Users per year | 91 (38%) | 132 (18%) | <0.00001 |
| Number of unique users | 195 | 354 | |
| Mean number of fills per user | 16.9 | 6.9 | <.0001 |
| Neurologic Agents | |||
| Mean Yearly Cost | $269 | $135 | .07 |
| Mean No. Users per year | 58 (24%) | 42 (6%) | <0.00001 |
| Number of unique users | 116 | 91 | |
| Mean number of fills per user | 12.9 | 11.8 | 0.57 |
| Anticholinergics | |||
| Mean Yearly Cost | $254 | $4.95 | <.0001 |
| Mean No. Users per year | 42 (18%) | 7 (1%) | <0.00001 |
| Number of unique users | 108 | 27 | |
| Mean number of fills per user | 6.2 | 2.8 | .0006 |
| Cystourethroscopy, with dilation of bladder for interstitial cystitis (general anesthesia) (CPT 52260) | 69 (29%) | 0 | <0.00001 |
| Cystourethroscopy, with dilation of bladder for interstitial cystitis (local anesthesia) (CPT 52265) | 2 (0.8%) | 0 | 0.01 |
| Cystourethroscopy (CPT 52000) | 77 (32%) | 21 (3%) | <0.00001 |
| Bladder irrigation, simple, lavage and/or instillation (CPT 51700) | 5 (2%) | 0 | 0.0001 |
| Cystourethroscopy, with biopsy (CPT 52204) | 33 (14%) | 0 | <0.00001 |
| Urodynamics** | 34 (14%) | 12 (2%) | <0.00001 |
*
includes individuals who underwent the selected procedures during entire the 5-year study period
**
includes the following CPT codes:
-
- 51725 (simple cystometrogram)- 51726 (complex cystometrogram)- 51736 (simple uroflowmetry)- 51741 (complex uroflowmetry)- 51772 (urethral pressure profile studies)- 51784 (non-needle electromyography studies of anal or urethral sphincter)- 51785 (needle electromyography studies of anal or urethral sphincter)- 51795 (voiding pressure studies)- 51797 (measurement of intra-abdominal voiding pressure)- 51798 (ultrasound measurement of post-void residual urine)