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. Author manuscript; available in PMC: 2009 May 15.
Published in final edited form as: Toxicol Appl Pharmacol. 2008 Jan 26;229(1):77–85. doi: 10.1016/j.taap.2008.01.005

Figure 2.

Figure 2

Lipid oxidation products measured in control and DEDC-exposed rat nerves. (A) MDA levels were determined in posterior tibial nerves by HPLC MDA values are means ± SEM for each time point (the number of nerves analyzed were n=26 for the control zero time point, n=8 for the 2 and 4-week time points and n= 12 for the 8-week time point) two separate analyses were performed per nerve and both were assayed in duplicate by HPLC, giving 4 values per nerve.. (B) F2-Isoprostane levels in sciatic nerve were determined by the modified method of Folch and quantified by GC/MS. Isoprostane values are means ± SEM for each time point (n=4, except for DEDC 8-week n=5). *p < 0.05 and+p < 0.01, One-way ANOVA and Dunnett Multiple Comparisons Test as compared to zero time point.