TABLE 2.
QTL associated with breed morphological characteristics
| Trait | Chromosome | Position (bp) | logP | Threshold (P < x) | No. of genes | Candidate genes |
|---|---|---|---|---|---|---|
| Short coat | CFA 25 | 17,862,111 | 3.88 | 0.01 | 5 | TNFRSF19 |
| CFA 32 | 7,806,734 | 5.43 | 0.001 | 1 | Fgf5 | |
| Ear bend | CFA 10 | 11,915,402 | 4.70 | 0.01 | 2 | |
| CFA 15 | 44,137,464 | 4.10 | 0.01 | 5 | ||
| CFA 32 | 14,508,914 | 4.12 | 0.01 | 9 | ||
| CFA 34 | 21,414,695 | 6.84 | 0.001 | 9 | ||
| Tail curve | CFA 1 | 81,302,720 | 4.40 | 0.01 | 1 | |
| CFA 9 | 14,626,755 | 3.92 | 0.01 | 13 | ||
| CFA 25 | 51,048,799 | 4.36 | 0.01 | 4 | COL6A3 | |
| CFA 38 | 6,614,004 | 3.94 | 0.01 | 0 | ||
| Snout angle | CFA 10 | 61,541,406 | 3.88 | 0.01 | 3 | |
| CFA 12 | 57,797,364 | 5.22 | 0.001 | 4 | ||
| Snout ratio | CFA 1 | 97,045,173 | 5.43 | 0.001 | 4 | |
| CFA 9 | 50,982,910 | 3.95 | 0.01 | 13 | ||
| CFA 12 | 57,797,364 | 4.07 | 0.01 | 4 | ||
| CFA 21 | 27,755,937 | 4.68 | 001 | 6 | ||
| CFA 32 | 32,959,130 | 4.76 | 0.01 | 10 | ||
| Head ratio | CFA 9 | 25,422,459 | 4.01 | 0.01 | 16 | IGFBP4 |
| CFA 22 | 10,294,335 | 4.84 | 0. 01 | 2 | ||
| CFA 34 | 21,414,695 | 6.13 | 0.001 | 9 | ||
| CFA 38 | 24,931,616 | 4.05 | 0.01 | 14 | ||
| Leg ratio | CFA 3 | 64,678,450 | 4.27 | 0.01 | 8 | RNF4, MXD |
| CFA 6 | 22,280,330 | 4.06 | 0.01 | 6 | ||
| Tail ratio | CFA 15 | 44,239,862 | 4.45 | 0.01 | 5 | |
| Neck ratio | CFA 9 | 24,032,840 | 5.00 | 0.001 | 17 | STAT3 |
As in Table 1, traits (see materials and methods) are presented together with the chromosome on which they are located, the position of the SNP with which they are associated, and the significance of the association (logP), number of known genes in the LD interval (400 kb), and genomewide P-value threshold exceeded. Genomewide significance threshold P-values for traits varied between 3.8 and 4.1 for P ≤ 0.01 and between 4.34 and 4.7 for P ≤ 0.001 (underlining). For more details, see supplemental Tables 4 and 5. The number of genes within 200 kb of the SNP that were investigated for candidate genes and the names of the candidate genes are listed.