Figure 4.—

Survivorship of TPI^sugarkill Pros26¹ double mutants: statistical analysis of median life span of mutants aged at (A) 29° and (B) 25°. (A) Pros26¹ TPI^sgk/sgk have a modest but significant increase in longevity compared to TPI^sgk/sgk animals at 29° (P < 0.05). (B) Flies aged at 25° show a nonsignificant improvement in longevity. The median life span of Pros26¹ TPI^sgk/sgk double mutants is still much reduced from that of heterozygous controls at both temperatures examined (P < 0.0001). In A and B, the error given is SEM, statistical comparison uses Student's t-test, and n = 120 animals in six independent populations for each genotype.