Figure 1.—

(a–c) Distribution of the [A2] phenotype frequency for three values of F_IS. Allele frequencies were simulated from a beta(a, a) with a = 1/(1 + 4Nm) = 0.5. When F_IS = 0 (a), the distribution corresponds to the Hardy–Weinberg proportions g_[A2] = q²; when F_IS = 1 (c), the phenotype distribution is the same as the allele distribution because g_[A2] = q. An intermediate mixture situation (b) is presented with F_IS = 0.5. These numbers show how multiple dominant loci contain information about F_IS in the shape of the phenotype distribution.