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SOD3−/− exacerbated TAC-induced myocardial oxidative stress, as demonstrated by a significantly greater decrease of the ratio of GSH:GSSG (B) and significantly greater increases of myocardial nitrotyrosine (NT) (A and B) and TBARS (B) in SOD3−/− mice as compared with wild-type mice (Wt). *P< 0.05 vs the corresponding control; #P< 0.05 vs Wt.
