Table 1. In vitro characterization of P. berghei blood stages (IC50 data) [nM].
Drug | WT | Plrx(-) |
Chloroquine | 35.7 (±12.5) | 33.4 (±6.3) |
Methylene blue | 50.6 (±9.6) | 55 (±10.5) |
Artemisinin | 87.1 (±4.6) | 79.2 (±23.5) |
Mefloquine | 50.1 (±21.1) | 41.5 (±10.4) |
Amodiaquine | 20.5 (±10.4) | 19.2 (±9.6) |