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. Author manuscript; available in PMC: 2009 Apr 1.
Published in final edited form as: Atherosclerosis. 2007 Apr 6;197(2):504–514. doi: 10.1016/j.atherosclerosis.2007.02.023

Figure 3.

Figure 3

Microscopic cross sections (10 µm) of the proximal aortic root were stained with sudan and counterstained with hematoxylin to reveal lipid deposition and quantified by digital morphometry for both ApoE+/−- IL-6−/− mice and ApoE+/−-IL-6+/− mice maintained on standard chow diet and inoculated weekly with Pg (CP)(fig-3c), on high fat diet and inoculated weekly with vehicle (HS)( (normal saline) fig-3f) and on high fat diet and inoculated weekly with P.g.(HP)( fig-3i) .The data is presented as percentage of total lumen of the proximal aorta occupied by lesions at 14 weeks and 24 weeks. Values represent mean±SD, *p <0.05 for ApoE+/−-IL-6−/−mice as compared to ApoE+/−-IL-6+/− mice in same condition on same diet. Abbreviations are as defined in text. Photomicrographs shown are representative images used to obtain the data presented in (Fig-3c, 3f & 3i), of proximal aortic lesions in ApoE+/−-IL6+/− and ApoE+/−-IL-6−/− mice maintained on standard chow diet and inoculated weekly Pg (CP)(fig-3a & 3b), on high fat diet and inoculated weekly with vehicle(normal saline) (HS)(fig-3d & 3e) and on high fat diet and inoculated weekly with P.g.(HP) ( fig-3g & 3h) for 24 weeks. Original magnifications 20X. Scale bar represents 0.5mm.