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. Author manuscript; available in PMC: 2009 Apr 1.
Published in final edited form as: Atherosclerosis. 2007 Apr 6;197(2):504–514. doi: 10.1016/j.atherosclerosis.2007.02.023

Table-2.

Cytokine profile

Cytokine Group 2 (CP) Group 3 (HS) Group 4 (HP) Cytokine Group 2 (CP) Group 3 (HS) Group 4 (HP) Cytokine Group 2 (CP) Group 3 (HS) Group 4 (HP)
AXL + + ++ IL-1β ++ ++ +++ MCP-1 +++ +++ ++++
BLC +++ +++ ++++ IL-2 + + + MCP-5 ++++ +++ ++++
CD-30L ++++ +++ ++ IL-3 ++ + + M-CSF ++ +++ +++
CD-40 ++++ +++ +++ IL-3Rb +++ ++ ++ MIG + + +
CRG-2 +++ ++ ++++ IL-4 MIP-1α ++ ++ +++
CTACK +++ ++ +++ IL-5 MIP-1β ++ ++ ++
CXL-16 +++ + ++ IL-6 MIP-1γ ++ + +
EOTAXIN +++ +++ ++++ IL-9 + + MIP-2 ++ + ++
EOTAXIN-2 +++ +++ ++++ IL-10 MIP-3β +++ +++ +++
FAS LIGAND + + + IL-12p70 ++ +++ ++++ MIP-3α
FRACTALKINE + ++ +++ IL-13 P-SELECTIN ++ +++ ++++
GCSF +++ + IL-17 + + RANTES ++ +++ ++
GM-CSF + ++ +++ KC + SCE +++ +++ +++
IFNγ + + + LEPTIN-R ++ +++ SDF-1α ++++ +++ +++
IGFBP-3 + + +++ LEPTIN ++ +++ TARC +++ +++ +++
IGFBP-5 +++ ++ ++++ LIX + + + TCA-3 ++++ ++++ ++++
IGFBP-6 ++ + ++++ L-SELECTIN ++ ++ +++ TECK ++ ++ +
IL-1α +++ ++++ ++++ LYMPHOTACTIN ++ ++ + TNF-α +++ +++ ++++
VCAM-1 +++ +++ ++++ TNFR-II ++ +++ +++ TBFR-I +++ ++ +++
VEGF ++++ +++ ++++ TPO +++ ++++ ++

Expression of cytokines in the ApoE+/-IL-6−/− group compared to the ApoE+/-IL-6+/− group. Results are presented for subgroups receiving a standard chow diet and inoculated with Pg (CP); a high fat diet and inoculations with vehicle (HS); and a high fat diet and inoculated with Pg (HP)

− Unchanged

< 20% INCREASE: +

21–40% INCREASE: ++

41–60% INCREASE: +++

≥61% INCREASE: ++++