Table 1.
Putative direct c-Myc targets: biological processes
| Probe Set ID | Gene Symbol | Gene Title | Biological process |
| 1420821_at | Sgpp1 | sphingosine-1-phosphate phosphatase 1 | apoptosis |
| 1428480_at | Cdca8 | cell division cycle associated 8 | cell cycle |
| 1435306_a_at | Kif11 | kinesin family member 11 | cell cycle |
| 1423903_at | Pvr | poliovirus receptor | cell-cell adhesion |
| 1422889_at | Pcdh18 | protocadherin 18 | cell-cell adhesion |
| 1427489_at | Itga8 | integrin alpha 8 | cell-matrix adhesion |
| 1419717_at | Sema3e | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E | development |
| 1448595_a_at | Bex1 | brain expressed gene 1 | development |
| 1422198_a_at | Shmt1 | serine hydroxymethyltransferase 1 (soluble) | amino acid metabolism |
| 1418483_a_at | Ggta1 | glycoprotein galactosyltransferase alpha 1, 3 | carbohydrate metabolism |
| 1421879_at | Mtmr1 | myotubularin related protein 1 | lipid metabolism |
| 1426575_at | Sgms1 | sphingomyelin synthase 1 | lipid metabolism |
| 1445103_at | Tmem23 | Transmembrane protein 23 | lipid metabolism |
| 1417300_at | Smpdl3b | sphingomyelin phosphodiesterase, acid-like 3B | lipid metabolism |
| 1421957_a_at | Pcyt1a | phosphate cytidylyltransferase 1, choline, alpha isoform | lipid metabolism |
| 1422702_at | Azin1 | antizyme inhibitor 1 | polyamine metabolism |
| 1417190_at | Pbef1 | pre-B-cell colony-enhancing factor 1 | NAD biosynthetic process |
| 1423088_at | Tmod3 | tropomodulin 3 | negative regulation of cell motility |
| 1420847_a_at | Fgfr2 | fibroblast growth factor receptor 2 | proliferation |
| 1415691_at | Dlg1 | discs, large homolog 1 (Drosophila) | proliferation |
| 1422966_a_at | Tfrc | transferrin receptor | proliferation |
| 1420924_at | Timp2 | tissue inhibitor of metalloproteinase 2 | proliferation |
| 1420020_at | Suz12 | suppressor of zeste 12 homolog (Drosophila) | proliferation |
| 1416657_at | Akt1 | thymoma viral proto-oncogene 1 | proliferation |
| 1420852_a_at | B3gnt2 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 | protein amino acid glycosylation |
| 1426342_at | Stt3b | STT3, subunit of the oligosaccharyltransferase complex, homolog B (S. cerevisiae) | protein amino acid glycosylation |
| 1425581_s_at | Galnt7 | UDP-N-acetyl-alpha-D-galactosamine: polypeptide N-acetylgalactosaminyltransferase 7 | protein amino acid glycosylation |
| 1415692_s_at | Canx | calnexin | protein folding |
| 1429502_at | Stch | stress 70 protein chaperone, microsome-associated, human homolog | protein folding |
| 1427074_at | Pcmtd2 | protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 | protein modification |
| 1426721_s_at | Tiparp | TCDD-inducible poly(ADP-ribose) polymerase | protein modification |
| 1439151_at | Msrb3 | methionine sulfoxide reductase B3 | protein repair |
| 1431361_at | Prcp | prolylcarboxypeptidase (angiotensinase C) | proteolysis |
| 1421857_at | Adam17 | a disintegrin and metallopeptidase domain 17 | proteolysis |
| 1422528_a_at | Zfp36l1 | zinc finger protein 36, C3H type-like 1 | regulation of mRNA stability |
| 1420975_at | Baz1b | bromodomain adjacent to zinc finger domain, 1B | regulation of transcription, DNA-dependent |
| 1421162_a_at | Nfia | nuclear factor I/A | regulation of transcription, DNA-dependent |
| 1423773_at | Gpbp1 | GC-rich promoter binding protein 1 | regulation of transcription, DNA-dependent |
| 1423441_at | Tfb2m | transcription factor B2, mitochondrial | regulation of transcription, DNA-dependent |
| 1422864_at | Runx1 | runt related transcription factor 1 | regulation of transcription, DNA-dependent |
| 1416018_at | Dr1 | down-regulator of transcription 1 | regulation of transcription, DNA-dependent |
| 1418280_at | Klf6 | Kruppel-like factor 6 | regulation of transcription, DNA-dependent |
| 1425465_a_at | Senp2 | SUMO/sentrin specific peptidase 2 | regulation of transcription, DNA-dependent |
| 1421908_a_at | Tcf12 | transcription factor 12 | regulation of transcription, DNA-dependent |
| 1434643_at | Tbl1x | transducin (beta)-like 1 X-linked | regulation of transcription, DNA-dependent |
| 1426531_at | Zmynd11 | zinc finger, MYND domain containing 11 | regulation of transcription, DNA-dependent |
| 1419976_s_at | Nfatc3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | regulation of transcription, DNA-dependent |
| 1432143_a_at | Hbp1 | high mobility group box transcription factor 1 | regulation of transcription, DNA-dependent |
| 1427418_a_at | Hif1a | hypoxia inducible factor 1, alpha subunit | regulation of transcription, DNA-dependent |
| 1421835_at | Mtap7 | microtubule-associated protein 7 | response to osmotic stress |
| 1415996_at | Txnip | thioredoxin interacting protein | response to oxidative stress |
| 1416467_at | Ddx3x | DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3, X-linked | RNA helicase activity |
| 1415807_s_at | Sfrs2 | splicing factor, arginine/serine-rich 2 (SC-35) | RNA splicing |
| 1425625_at | Il13ra1 | interleukin 13 receptor, alpha 1 | signal transduction |
| 1426892_at | Utrn | utrophin | signal transduction |
| 1433706_a_at | Ptplad1 | protein tyrosine phosphatase-like A domain containing 1 | signal transduction |
| 1424947_at | Dync1li1 | dynein cytoplasmic 1 light intermediate chain 1 | signal transduction |
| 1425538_x_at | Ceacam1 | CEA-related cell adhesion molecule 1 | signal transduction |
| 1420918_at | Sgk3 | serum/glucocorticoid regulated kinase 3 | signal transduction |
| 1437295_at | Pkn2 | protein kinase N2 | signal transduction |
| 1416504_at | Ulk1 | Unc-51 like kinase 1 (C. elegans) | signal transduction |
| 1418489_a_at | Calcrl | calcitonin receptor-like | signal transduction |
| 1421239_at | Il6st | interleukin 6 signal transducer | signal transduction |
| 1420814_at | Gdi2 | guanosine diphosphate (GDP) dissociation inhibitor 2 | signal transduction |
| 1420696_at | Sema3c | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | signal transduction |
| 1418022_at | Narg1 | NMDA receptor-regulated gene 1 | transcription |
| 1420307_a_at | Pitpnb | phosphatidylinositol transfer protein, beta | transport |
| 1419970_at | Slc35a5 | solute carrier family 35, member A5 | transport carbohydrate |
| 1421839_at | Abca1 | ATP-binding cassette, sub-family A (ABC1), member 1 | transport cholesterol |
| 1417622_at | Slc12a2 | solute carrier family 12, member 2 | transport ion |
| 1418257_at | Slc12a7 | solute carrier family 12, member 7 | transport ion |
| 1416832_at | Slc39a8 | solute carrier family 39 (metal ion transporter), member 8 | transport metal ion |
| 1426712_at | Slc6a15 | solute carrier family 6 (neurotransmitter transporter), member 15 | transport neurotransmitter |
| 1421641_at | Slc6a2 | solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2 | transport neurotransmitter |
| 1421167_at | Atp11a | ATPase, class VI, type 11A | transport phospholipid |
| 1423597_at | Atp8a1 | ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 | transport phospholipid |
| 1428065_at | Slc44a2 | solute carrier family 44, member 2 | transport protein |
| 1416375_at | Ap3m1 | adaptor-related protein complex 3, mu 1 subunit | transport protein |
| 1436508_at | 2410014A08Rik | RIKEN cDNA 2410014A08 gene | transport protein |
| 1416189_a_at | Sec61a1 | Sec61 alpha 1 subunit (S. cerevisiae) | transport protein |
| 1426775_s_at | Scamp1 | secretory carrier membrane protein 1 | transport protein |
| 1420867_at | Tmed2 | transmembrane emp24 domain trafficking protein 2 | transport protein |
| 1421955_a_at | Nedd4 | neural precursor cell expressed, developmentally down-regulted gene 4 | ubiquitin cycle |
| 1416680_at | Ube3a | ubiquitin protein ligase E3A | ubiquitin cycle |
| 1426495_at | 2410042D21Rik | RIKEN cDNA 2410042D21 gene | ? |
| 1419152_at | 2810417H13Rik | RIKEN cDNA 2810417H13 gene | ? |
| 1421603_a_at | Ceacam2 | CEA-related cell adhesion molecule 2 | ? |
| 1417821_at | D17H6S56E-5 | DNA segment, Chr 17, human D6S56E 5 | ? |
| 1423557_at | Ifngr2 | interferon gamma receptor 2 | ? |
| 1421064_at | Mpp5 | membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) | ? |
| 1421814_at | Msn | moesin | ? |
| 1423479_at | Nol11 | nucleolar protein 11 | ? |
| 1426806_at | Obfc2a | oligonucleotide/oligosaccharide-binding fold containing 2A | ? |
| 1424778_at | Reep3 | receptor accessory protein 3 | ? |
The table gives the 94 genes which are putatively directly regulated by c-Myc and the corresponding biological processes they are involved in. In this table, the 15 targets stored already in the Myc Target Database are marked bold.