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. Author manuscript; available in PMC: 2009 May 10.
Published in final edited form as: Virology. 2008 Feb 14;374(2):304–314. doi: 10.1016/j.virol.2008.01.013

FIGURE 5. Identification of regions in HPV16 that is able to substitute for replication element.

FIGURE 5

FIGURE 5

(A) Short-term replication of HPV16 library constructs in pGFP vector. Hirt-extracted DNA at 4 days posttransfection was analyzed by Southern blot after overnight digestion with DpnI and XhoI. (B) The loss rates of each plasmid was determined as the relative loss rate per cell generation. The loss rates of each plasmid was compared to that of the most stable constrtuct.