Table 3.

Cox regression analysis of multi-SNP haplotype–tagged SNPs and ovarian cancer survival

Gene	Tagging SNPs	Haplotype*	Tagged SNPs	Missing data†	Haplotype frequency	HR (95% CI)	P
CDK6	rs4729049, rs992519	11	rs2374594, rs6975474, rs2374589, rs10246604	2	0.068	1.00 (0.75-1.32)	1.0
	rs3217862, rs3217820	00	rs3217827 rs3217881	3	0.48	1.00 (0.88-1.14)	1.0
	rs3217869, rs3217852	00	rs3217830 rs3217896	2	0.37	1.00 (0.87-1.15)	1.0
CCND2	rs3217926, rs3217925, rs3217916	000	rs3217907	7	0.35	1.00 (0.87-1.15)	1.0
	rs3217926, rs3217936	00	rs4625554	5	0.30	1.00 (0.86-1.19)	1.0

^*0 represents common allele of the tagging SNP in the haplotype; 1 represents rare allele of the tagging SNP in the haplotype.

^†Number of subjects missing 50% or more of the SNP data for each haplotype.