Table 3.
Arterial free fatty acid and β-hydroxybutyrate concentrations (μmol/l), net hepatic balances (μmol·kg−1·min−1), and hindlimb balances (μmol/min)
Group and parameter | Basal | Low Insulin | High Insulin |
---|---|---|---|
Free Fatty Acids | |||
Arterial plasma | |||
NP | 862 ± 74 | 547 ± 90 | 156 ± 32* |
P | 830 ± 65 | 592 ± 49 | 172 ± 27* |
Net hepatic uptake | |||
NP | 2.8 ± 0.6 | 1.9 ± 0.7 | 0.4 ± 0.2* |
P | 2.6 ± 0.4 | 2.2 ± 0.5 | 0.4 ± 0.1* |
Net hindlimb balance | |||
NP | 2.8 ± 4.3 | −0.6 ± 2.2 | −1.2 ± 0.9 |
P | 0.5 ± 3.6 | −0.7 ± 2.1 | −0.6 ± 1.3 |
β-Hydroxybutyrate | |||
Arterial blood | |||
NP | 39 ± 13 | 29 ± 10 | 7 ± 2* |
P | 68 ± 19 | 29 ± 7* | 5 ± 1* |
Net hepatic output | |||
NP | 1.6 ± 0.7 | 1.2 ± 0.5 | 0.2 ± 0.1* |
P | 1.5 ± 0.3 | 0.7 ± 0.2* | 0.1 ± 0.1* |
Net hindlimb uptake | |||
NP | 2.1 ± 0.7 | 1.9 ± 0.6 | 0.6 ± 0.2* |
P | 2.7 ± 0.5 | 1.5 ± 0.4 | 0.0 ± 0.2*† |
Values are means ± SE for the 3 time points during each period; n = 9 per group. Negative values for balance data indicate net uptake.
P < 0.05 vs. basal;
P < 0.05 vs. NP.