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. Author manuscript; available in PMC: 2008 Nov 23.
Published in final edited form as: Science. 2008 May 1;320(5879):1088–1092. doi: 10.1126/science.1157121

Fig. 3. Rescue of the mask phenotype by BAC transgenesis.

Fig. 3

Four founders (designated 49-52 OQ) were produced by microinjecting a BAC clone bearing the WT Tmprss6 sequence into single-cell embryos homozygous for the mask mutation. Hemoglobin and serum iron levels in each of the founders, in blood sampled at 4 weeks of age. B6 controls, age-matched C57BL/6J mice, N=4. Non-transgenic controls, Tmprss6msk/msk littermates that lacked the transgene, N=4. Error bars indicate 1 SEM.