Figure 1.

Immunostaining of the gastric corpus (A–E) and antral (F–J) mucosae with anti-mucin monoclonal antibodies. Gastric tissues were obtained from control rats (A, F), rats treated with 5-fluorouracil (5-FU) alone (B, G), rats treated with omeprazole (Ome+ 5-FU (C, H), rats treated with lansoprazole (Lan)+5-FU (D, I), and rats treated with lafutidine (Laf)+5-FU (E, J). Notice that surface epithelial mucus cells in the corpus show positive staining with RGM21, and those in the antrum show positive staining with RGM26. Original magnification ×25.