Table 3.
Hippocampal and posterior cingulate cortex MRglc measures by MCI subgroups.
| Hip (μmol/g/min) | PCC (μmol/g/min) | |||||
|---|---|---|---|---|---|---|
| Baseline | Last exam a | Annual rate (%) | Baseline | Last exam a | Annual rate (%) | |
| NL-NL | 30.8(5.3) | 27.8(3.6) | −0.8(0.3) | 51.2(9.6) | 42.9(6.9) | −1.3(0.8) |
| NL-MCI | ||||||
| Non-amnestic | 27.1(4.1)* | 24.3(4.6)** | −1.99(0.5)** | 51.3(9.3) | 38.7(5.6) | −0.78(0.9) |
| Memory deficits 1SD<NL | 25.0(4.9)* | 23.9(2.1)** | −2.28(0.4)** | 47.4(6.8) | 38.5(6.5) | −2.21(0.8) |
| Amnestic | 26.6(3.6)* | 22.01(3.3)** | −2.46(0.5)** | 47.9(7.8) | 32.9(2.8)* + º | −2.37(0.8) |
Values are mean MRglc (SD). Abbreviations: Hip = hippocampus; PCC = posterior cingulate cortex.
*
Significantly lower than NL-NL, p≤.05
**
Significantly lower than NL-NL, p≤.01
+
Significantly lower than non-amnestic MCI, p≤.05
º
Significantly lower than MCI with memory deficits 1SD<NL, p≤.05
a
Longitudinal FDG PET examinations were performed in all 19 NL-MCI and 30 NL-NL.