Figure 5.

Forskolin-stimulated ³H-cAMP accumulation in CHO-H3-SPAP cells in response to a) histamine, b) immethridine, c) impentamine d) proxyfan and e) burimamide in the absence and presence of 10 nM clobenpropit. Bars show basal ³H-cAMP accumulation, that in response to 10 μM forskolin alone and that in response to 10 nM clobenpropit in the presence of 10 μM forskolin. Data points are mean ± s.e.m. of triplicate values from single experiments that are representative of a) 5, b) 5, c) 4, d) 5 and e) 4 separate experiments.