Table 1.

Functional annotations associated with the upregulated LPS- and heat shock-responsive genes, respectively.

	LPS	Heat Shock
Pathway (p value)	• Apoptosis signaling (1.5E-10)	• Apoptosis signaling (1.8E-3)
	• Inflammation mediated by chemokine and cytokine signaling (2.1E-7)	• Angiogenesis (3.2E-2)
	• Toll receptor signaling (9.6E-6)
	• Integrin signaling (1.4E-2)
Biological process (p value)	• Immunity and defense (2.2E-25)	• Protein folding (2.1E-14)
	• Signal transduction (5.8E-23)	• Protein metabolism and modification (1.7E-10)
	• Intracellular signaling cascade (3.0E-16)	• Stress response (1.8E-10)
	• Cell surface receptor mediated signaling (2.7E-10)	• Protein phophorylation (1.7E-6)
	• Cytokine and chemokine mediated signaling (3.1E-10)	• Immunity and defense (2.0E-5)
Molecular function (p value)	• Signaling molecule (1.4E-10)	• Chaperone (1.2E-16)
	• Other transcription factor (3.0E-7)	• Hsp 70 family chaperone (1.9E-7)
	• Chemokine (3.3E-6)	• Protein kinase (2.8E-6)
	• Cytokine receptor (1.2E-5)	• Transcription factor (2.0E-4)
	• Select regulatory molecule (8.9E-5)	• Chaperonin (1.2E-3)

Data are based on the PANTHER database using the default parameters in the database and Bonferroni correction for multiple comparisons.