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. 2008 Feb 1;116(6):703–708. doi: 10.1289/ehp.10978

Figure 2.

Figure 2

Contrasting false-color micro-XRF element maps corresponding to the S, As, and Se panels from Figure 1. Dashed lines in upper right corners demarcate the boundary between the epidermis and a tiny region of dermis. These images emphasize the differing subcellular distributions of As and Se in mice given As(III) only, particularly in the overlay, where As is clearly evident throughout the nucleus (excluding the nucleolus), whereas Se is concentrated more in the peripheral regions of the cells, where cellular and nuclear membranes tend to be located in these heavily UVR-damaged cells.