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. 2008 Feb 1;116(6):703–708. doi: 10.1289/ehp.10978

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Micro-XRF spectra of skin from mice exposed for 14 days to As(III) only, Se(IV) only, or As(III) + Se(IV) compared with control. Abbreviations: Cl, chlorine; Fe iron. The control shows no As and a small Se peak. A definitive As peak is detected in the As-only skin just to the left of the Se peak. The Se peak is increased by a factor of about 2 in the Se-only and the As + Se skin. In the As + Se skin, the As peak is completely missing. Clearly, the As has been blocked from entering the skin by the Se even at this early time point.