Table 4.

Plasma t-PA antigen concentrations after exposure to filtered air or CAPs.

	Air				CAPs
Bradykinin (pmol/min)	0	100	300	1,000	0	100	300	1,000
tPA (ng/mL)
Noninfused arm	7.6 ± 0.5	7.4 ± 0.5	7.9 ± 0.5	8.5 ± 0.5	7.2 ± 0.5	7.3 ± 0.6	7.7 ± 0.5	8.6 ± 0.5
Infused arm	7.3 ± 0.5	8.8 ± 0.5	9.7 ± 0.6	14.3 ± 1.2*	7.3 ± 0.6	8.6 ± 0.6	9.5 ± 0.7	14.2 ± 1.1*
Difference	−0.4 ± 0.2	1.4 ± 0.4	1.9 ± 0.4	5.8 ± 1.1*	0.1 ± 0.2	1.3 ± 0.4	1.7 ± 0.4	5.7 ± 1.0*
Net t-PA release (ng/100 mL tissue/min)	−1 ± 1	11 ± 3	20 ± 5	90 ± 18*	0 ± 1	12 ± 4	24 ± 6	104 ± 19*

Values shown are mean ± SE (n = 24).

^*p < 0.0001 (ANOVA; dose response).