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. Author manuscript; available in PMC: 2009 Feb 1.
Published in final edited form as: Psychoneuroendocrinology. 2008 Feb;33(2):162–177. doi: 10.1016/j.psyneuen.2007.10.012

Figure 5.

Figure 5

Prenatal stress subtly decreases anxiety-like behavior in adult LR offspring, while HR behavior remains unaffected. Adult HR offspring, regardless of previous exposure to prenatal stress, were more willing to explore the anxiogenic open arms of the elevated plus maze, spending greater time in the open arms (A) and making more open arm entries (C) compared to both LR groups (N=10-12 per group). Adult LR control animals displayed the greatest latency to initially enter the open arms compared to all other groups (B). Interestingly, LR animals previously exposed to prenatal stress behaved more like HR rats and exhibited reduced latency to enter the open arms compared to LR controls (B). Overall, HR and LR adults did not show differences in activity on the elevated plus maze, assessed via the number of closed arm entries made during the 5-min test (D). * indicates p<0.05.