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. Author manuscript; available in PMC: 2009 May 15.
Published in final edited form as: Bioorg Med Chem Lett. 2007 Dec 5;18(10):3068–3071. doi: 10.1016/j.bmcl.2007.11.130

Table 1.

Measured IC50 values of K-26 and analogs

compound IC50(nM)
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1a, (K-26) Ac-l-Ile-l-Tyr-R-AHEP 14.4
1b,Ac-l-Ile-l-Tyr-S-AHEP 139
1c, Ac-l-Ile-l-Tyr-R-AHEP(OEt)2 3.83 × 105
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14a, l-Ile-l-Tyr-R-AHEP 234.3
14b, l-Ile-l-Tyr-S-AHEP 5.46 × 104
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15a, Ac-l-Ile-l-Tyr-l-Tyr 2.1 × 104
15b, Ac-l-Ile-l-Tyr-d-Tyr 2.0 × 106
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16a, l-Ile-l-Tyr-l-Tyr 2.36 × 105
16b, l-Ile-l-Tyr-d-Tyr > 106
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