Table 3.

Animal models and antioxidants in the prevention of atherosclerosis:

Model	Antioxidant(s) used
LDL Receptor Knockout mice	Vitamin E, beta-carotene, vitamin C, probucol, S-nitroso-N-acetylcysteine, nitric oxide-releasing aspirin, 2,3-dihydro-5-hydroxy-2, 2-dipentyl-4,6-di-tert-butylbenzofuran.
Apolipoprotein E knockout mice	N-acetylcysteine, vitamin E, probucol, N,N'-diphenyl 1,4-phenylenediamine (DPPD), calcium channel blockers- lacidipine, disodium ascorbyl phytostanyl phosphate, taurine, tocotrienol, catechins.
WHHL Rabbits	Probucol, vitamin E, and fluvastatin, an HMG-CoA (hydroxy-3-methylglutaryl coenzyme A), ubiquinone-10, N-acetylcysteine, astaxanthin, water-soluble vitamin E derivative, N,N'-diacetyl-L-cystine.
Cholesterol-fed NZW rabbits	Probucol, vitamin E, polyphenol, U74006F, BHT, N,N'-diphenyl 1,4-phenylenediamine (DPPD)
Cholesterol-fed hamsters	Isoflavones, vegetable extract (Oxxynea), alpha-lipoic acid (ALP), Vitamin E, Green tea, probucol, grape extracts.
Cholesterol-fed guinea pigs	Vitamin C, Vitamin E, Huajiao volatile oil
Monkeys	Vitamin E, probucol, various soy components.