Fig. (8).

Effect of PGE₁ and iloprost on the hva (=high voltage activated) Ca²⁺ current. A: Hva Ca²⁺ current at +15 mV in control and 0.2 μM PGE₁. B: Hva Ca²⁺ current at +15 mV in control and 50 nM iloprost. C: Peak current vs pulse potential from a different cell in control, 3 μM PGE₁ and wash. D: Same for current at end of 160 ms pulses. Ruptured patch with bath containing 10 mM Ca²⁺ and K⁺-free pipette solution. Holding potential -70 mV. Temperature 20-21ºC. From [71].