Fig. (2).

Parallel genotyping and DNA copy number change analysis of testicular germ cell tumor. A). SNP genotype patterns along the chromosomes of two cases of non-seminomas with paired normal controls. From top to bottom, the cases presented are 5T (tumor), 5N (normal), 7T and 7N. It shows acquired large homozygous chromosome regions (HCRs, chromosome regions with 98% or greater homozy-gosities in a minimum region of 50 contiguous SNPs) on chromosome 2q, 5, 10, 11, 13 and 14 in case 5T and chromosome 4, 8q and 13 in case 7T. For each chromosome, two blue lines represent either AA or BB homozygous calls. The red line represents AB heterozygous calls and the grey line on the bottom shows SNPs not called. B). DNA copy number changes along the chromosomes of the same two tumors. The signal intensity of the tumor samples is normalized against the normal controls. The top case is 5T and the bottom case is 7T.