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. 2008 May 27;9:249. doi: 10.1186/1471-2105-9-249

Figure 2.

Figure 2

a Relative improvement over PSI-BLAST as a function of the parameters used (Methods). b ROC curves obtained for PSI-BLAST and ModFun, using different expansion and filter cutoffs (solid line, PSI-BLAST; filled circles, ModFun with expansion cutoff of 40% and filter cutoff of 55%; empty circles, ModFun with expansion cutoff of 50% and filter cutoff of 55%; stars, ModFun without expansion nor filter). Labels in the plot indicate specificity and sensitivity at the 40% identity threshold for PSI-BLAST and ModFun with optimal parameters (expansion cutoff of 40%, filter cutoff of 55%).