Table 1.
Proteins Implicated in Multiple Sclerosis and Its Animal Models
| protein | accession number |
peptide count |
ratio | p-value | multiple sclerosis |
EAE |
|---|---|---|---|---|---|---|
| Apolipoprotein D | P23593 | 3 | 1.4 | 9.1E-3 | Reindl et al.71 Chabas et al.72 |
Alt et al.60 |
| Apolipoprotein E | P02650 | 5 | 2.5 | 3.0E-3 | Carlin et al.73 Hammack et al.8 |
Alt et al.60 |
| Ca2+/Calmodulin kinase IIα | P11275 | 2 | 0.6 | 3.1E-2 | Lock et al.1 | |
| Cathepsin B | P00787 | 3 | 1.5 | 3.3E-2 | Bever et al.74 Bever and Garver75 |
|
| Ceruloplasmin | P13635 | 7 | 2.8 | 2.4E-3 | Hunter et al.76 | Alt et al.60 |
| Complement C3 | P01026 | 12 | 2.2 | 3.8E-3 | Gay48 | Alt et al.60 Ibrahim et al.39 |
| Cystatin C | P14841 | 2 | 2.5 | 3.0E-2 | Irani et al.77 Tajouri et al.38 |
|
| Excitatory amino acid trasporter 2 | P31596 | 6 | 0.7 | 2.6E-2 | Pitt et al.47 Vallejo-Illarramendi et al.78 |
Ohgoh et al.79 |
| Fibronectin | P04937 | 5 | 2.6 | 3.3E-2 | Sobel and Mitchell80 Van Horssen et al.81 |
Ibrahim et al.39 |
| Filamin A | IPI00409539 | 2 | 1.8 | 4.4E-2 | Lock et al.1 | Ibrahim et al.39 |
| Hemopexin | P20059 | 7 | 2.1 | 8.3E-3 | Hammack et al.8 | |
| α2-HS Glycoprotein | P24090 | 3 | 2.3 | 1.0E-2 | Donelan et al.82 | |
| IgG-2A chain C region | P20760 | 2 | 3.2 | 2.2E-2 | Lock et al.1 | |
| L-Plastin | Q5XI38 | 6 | 2.3 | 1.5E-2 | Alt et al.60 | |
| α2-Macroglobulin | P06238 | 2 | 2.3 | 3.8E-2 | Jensen et al.44 | Ibrahim et al.39 |
| Moesin | O35763 | 6 | 1.5 | 3.1E-2 | Tajouri et al.40 | Ibrahim et al.39 |
| Peptidyl-prolyl cis-trans isomerase B | P24368 | 2 | 1.4 | 4.2E-2 | Ramanathan et al.83 | |
| Proteasome activating complex subunit | Q63797 | 2 | 2.6 | 2.7E-3 | Ibrahim et al.39 | |
| Serum albumin | P02770 | 30 | 3.4 | 1.4E-2 | Hammack et al.8 | Juhler et al.84 |
| Serotransferrin | P12346 | 20 | 2.5 | 1.4E-2 | LeVine et al.85 Tajouri et al.38 |
|
| Vimentin | P31000 | 10 | 1.5 | 5.5E-3 | Holley et al.86 Yamada et al.87 |