Table 1.
Study Characteristics by Study Sample
| Framingham Heart Study | ARIC whites | ||
| Examination 7 | Visit 1 | Visit 4 | |
| Characteristic | |||
| Sample size n | 1007 | 11217 | 8717 |
| Age, years | 58.5 (9.6) | 54.4 (5.7) | 63.1 (5.6) |
| Male, % | 49.1 | 47.2 | 46.3 |
| Systolic blood pressure, mmHg | 125 (18.5) | 118.5 (17) | 125.5 (18) |
| Antihypertensive medication, % | 31.2 | 25.8 | 31.4 |
| Diabetes mellitus, % | 11.2 | 9.1 | 13.9 |
| Body mass index, kg/m2 | 28.4 (5.8) | 27.0 (4.9) | 28.3 (5.2) |
| Current smokers, % | 14.2 | 24.8 | 14.1 |
| High density lipoprotein cholesterol, mg/dl | 52.6 (16.1) | 50.4 (16.8) | 49.0 (16.3) |
| Serum creatinine, mg/dl | 0.88 (0.28) | 0.85 (0.20) | 0.91 (0.24) |
| eGFR, ml/min/1.73 m2 | 86.6 (19.8) | 89.6 (17.9) | 80.5 (16.9) |
| Prevalent CKD*, n (%) | 80 (8.0) | 449 (4.0) | 756 (8.7) |
| Incident CKD†, n | N/A | N/A | 843 |
| Serum cystatin C, mg/l | 0.96 (0.24) | N/A | N/A |
Data are presented as mean (standard deviation) for continuous and proportion for categorical variables for individuals with information on all characteristics available at FHS Offspring exam 7 and ARIC visits 1 and 4. *CKD was defined as eGFR <59 ml/min/1.73 m2 (women) and <64 ml/min/1.73 m2 (men). †For definition of incident CKD and duration of follow-up see methods section. Abbreviations: eGFR: estimated glomerular filtration rate, CKD: chronic kidney disease.