Table 1.
Summary of approaches used to calculate the continuous metabolic syndrome score in pediatric epidemiological research.
Study | Obesity | Lipids | Glucose or Insulin | Blood Pressure | Other | Statistical approach |
Bogolusa Heart Study [21] | - | TC:HDL | Insulin | SBP | Sum of the individual rankings by age-, sex-, and race-specific levels | |
Young Danes [28] | Skinfolds | TC, HDL-C, TG | - | SBP and DBP | smoking | Upper centiles |
Cardiovascular Risk in Young Finns [22] | - | TC and HDL-C | - | DBP | Upper tertile | |
European Youth Heart Study [20] | Skinfolds | HDL-C and TG | Glucose and insulin | Average of SBP and DBP | Sum of six Z scores divided by 6 | |
European Youth Heart Study [19] | Skinfolds | TG and TC:HDL-C | HOMA | SBP | Aerobic fitness | Sum of Z scores |
Corpus Christi Child Heart Study [23] | BMI | HDL-C and TG | Insulin | SBP | 2 approaches: 1) sum of Z scores, and 2) principal components analysis | |
Quebec Family Study [24] | Skinfolds | HDL-C, TG, and TC:HDL-C | Glucose | MAP | principal component analysis | |
Aerobic Center Longitudinal Study [27] | WC | HDL-C and TG | Glucose | MAP | Sum of age-standardized residuals | |
Australian Health and Fitness Study [34] | WC | HDL-C and TG | - | MAP | Sum of age-standardized residuals | |
Physical Activity across the Curriculum [38] | WC | HDL-C and TG | HOMA | MAP | Sum of age-, sex-, and race-standardized residuals |
BMI, body mass index; WC, waist circumference; TC, total cholesterol; HDL-C, high density lipoprotein-cholesterol; TG, triglycerides; HOMA, homeostasis model assessment; SBP, systolic blood pressure; DBP, diastolic blood pressure; MAP, mean arterial pressure.