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Correlation of blood levels of HCV RNA and levels of IFN-α secreted by PBMC from individual HCV-infected donors (n = 15) after 48 hr culture with A-Class (black symbols) or C-Class (white symbols) CpG (6 μg/ml). The 7 HCV subjects with low viral load (< 600,000 IU/ml) had R2 values of 0.07 and 0.005 for the A- and C-Class CpG respectively.
