Table 1.
Group 1 | Group 2 | Group 3 | |
---|---|---|---|
Day 0 | EB injection | EB injection | EB injection |
Days 2–5 | BrdU Pulse | ||
Day 7 | Nanosphere injection | Nanosphere injection | Nanosphere injection |
Day 9 | Sacrifice | ||
Day 14 | Sacrifice | ||
Day 35 | Sacrifice |
Group 1: Animals evaluated for astrogliosis in contralateral VLF following CNTF (n=4) and blank (n=4) nanosphere injection.
Group 2: Animals evaluated for survival of endogenous BrdU-pulsed OPCs following CNTF (n=4) and blank (n=4) nanosphere injection.
Group 3: Animals evaluated for presence of mature oligodendrocytes following CNTF (n=4) and blank (n=4) nanosphere injection into EB lesions.