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. 2008 Apr 4;283(14):9414–9423. doi: 10.1074/jbc.M705026200

TABLE 3.

vFe-O2 and dissociation rate constants (koff) for HbIILp, HbILp, and HbILp mutants

Heme protein vFeO2 koff
cm−1 s−1
HbI (Gln(E7), Phe(B10), Phe(E11)) 567 61.0a
HbIr (Gln(E7), Phe(B10), Phe(E11)) 567 140.0
HbIGln(E7) → Val 563 500.0
HbIGln(E7) → Asp 563 375.0
HbIGln(E7) → His 569 3.0
HbIPhe(B10) → Tyr 571 0.60
HbII (Gln(E7), Tyr(B10), Phe(E11)) 572 0.11a
a

From Ref. 2.