Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Proposed biosynthetic pathway for NAEs including AEA. Both O-acyl chains are removed from N-arachidonoyl phosphatidylethanolamine (NArPE) by Abh4 yielding GP-NArE. The phosphodiester bond of GP-NArE is then hydrolyzed by a phosphodiesterase (identified herein as GDE1) to release free anandamide and glycerol 3-phosphate.
