TABLE 5.
QTL for glucose identified in human homologous regions and other mouse crosses
| QTL | Chr | 95% CI | Human QTL Homologous Regiona (Ref) | Coincident QTL Crossb (Ref) |
|---|---|---|---|---|
| Mb | ||||
| Bglu4 | 2 | 60–90 | 2q241-311 (34) | BKS × C3H (35) |
| Bglu5 | 2 | 120–175 | 20p112-q131 (36) | B6 × C3H (37) |
| Bglu6 | 4 | 21–45 | 9p21-13 (38) | — |
| none | 7 | 26–78 | 19q12-19q134 (38, 39) | — |
| Bglu7 | 10 | 74–100 | 21q22 (40), 22q11-12 (41) | SM × A/J (42) |
| Bglu8 | 15 | 15–70 | 8q22-24 (40) | Balb/cJ × KK/Ta (F) (43), Akita × A/J (44) |
| Bglu9 | 17 | 0–45 | 6p213-212 (38), 6q253-qter (41) | B6 × NOD (45) |
| Bglu10 | 18 | 0–50 | 10p121-112, 5q31-32 (36),18q12-23(46) | NON × NZO (47), SMxA/J (42) |
a
Human homologous region of the mouse QTLs were retrieved from the Genome Orthology Map at http://www.informatics.jax.org/reports/homologymap/mouse_humans.html.
b
The strains that contribute the high allele are in boldface. For the NON × NZO cross, we obtained the high allele from Dr. Ed Leiter.