Fig. 7.

Blood glucose, cholesterol, and triglyceride levels in fasted and fed adenovirus-infected mice. C57BL/6 mice were infected with recombinant adenovirus expressing luciferase (Ad-Luc) or Elovl-5 (Ad-Elovl5) as described in the legend to Fig. 3 and Materials and Methods. Four days after infection, all mice were starved overnight. The next morning (8:00 AM), half of the mice in each group were fed chow. Fasted mice were euthanized at 8:00 AM, and fed mice were euthanized 4 h after initiating feeding (12:00 PM). Blood glucose (A), cholesterol (B), and triglycerides (C) were measured in fasted and fed animals (see Materials and Methods). Results are reported as means ± SD (n = 4 per group). Statistical differences as determined by ANOVA in blood glucose, triglycerides, and cholesterol between the four groups are noted. * P < 0.05, fasted versus fed for either the Ad-Luc or Ad-Elovl5 group, by ANOVA.