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. Author manuscript; available in PMC: 2009 Jan 1.
Published in final edited form as: Int J Biochem Cell Biol. 2008 Mar 14;40(6-7):1238–1245. doi: 10.1016/j.biocel.2008.03.003

Table 2.

Antiprotease Activities

A1AT Inhibits NE, cathepsin G
SLPI Inhibits NE, cathepsin G
Inhibits TLR activation
Inhibits NF-κB activation
Increases ASL glutathione levels
Elafin Inhibits NE
Has antimicrobial activity
Activates dendritic cells
Monocyte/neutrophil elastase inhibitor Inhibits NE, cathepsin G, proteinase 3
Has anti-inflammatory effect in vivo
Promotes clearance of lung P. aeruginosa in vivo