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. 2008 Jun 10;8:e32.

Table 2.

Synopsis of sulfur mustard pathology

Gross pathology Histopathology and cytopathology Molecular pathology
Erythema Cellular infiltrate cytokines (IL-1, IL-6, IL-8, and TNF-α)
Pain Separation of cellular layers Prostaglandins
Blisters Apoptosis Matrix metalloproteinases
Pseudomembranes Necrosis Serine proteases
Ulcers   Caspase activation
Impaired wound healing   DNA adducts
    Cell cycle arrest
    Oxidative stress
    Intracellular Ca++ increase
    Impaired energy metabolism