Figure 2. IL-2 promotes proliferation and survival of FOXP3+ T cells.
CD4+CD25− T cells were stained with CFSE and activated with irradiated APC and soluble anti-CD3 and anti-CD28 in the presence of media or 200 IU/ml IL-2. IL-2 was added on days 0, 3, and 6 (A). The frequency of CD25+FOXP3+ T cells was calculated 10 days following activation with irradiated APC and soluble anti-CD3 (n = 10) (B).