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. 2008 Jul 2;3(7):e2606. doi: 10.1371/journal.pone.0002606

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This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration, which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

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S = schools closed; CTsd = child/teenager social distancing; ASsd = adult/senior socials distancing; Q = household quarantine; T = antiviral treatment; P = antiviral prophylaxis of household members; PEx = extended antiviral prophylaxis. For Ferguson-like disease manifestation and implementation threshold when 10 cases are diagnosed. Case-based interventions are applied directly to or around diagnosed individuals to limit transmission and are: Q, T, P, and PEx. Network-based interventions are applied to affect links and contacts between individuals throughout the entire network and are: S, CTsd, ASsd (where adults continue to attend work, although at a 50% reduction in contacts at the workplace). Case-based interventions vertical; network-based interventions horizontal. Green shading denotes infection rates ≤10 percent of population. Pink shading denotes infection rates between 10 and 25 percent.