Table 3. Summary of biophysical properties of mouse Cav1.4wtand Cav1.4nob2 constructs recorded with 20 mM Ba2+ as charge carrier.
| Vact (mV) | Gmax (nS) | S (mV) | Erev (mV) | Vinact (mV) | z | |
| Cav1.4wt | −3±4 (11) | 4±3 (11) | 9±1 (11) | 44±6 (11) | −18±11 (11) | 1.9±0.6 (11) |
| Cav1.4nob2 | −1±4 (13) | 3±1 (13) | 8.2±0.8 (13) | 45±6 (13) | −22±10 (12) | 3±3 (12) |
| Cav1.4wt (s.s.) | −1±6 (4) | 4±3 (4) | 9±1 (4) | 44±7 (4) | −22±9 (4) | 2.0±0.6 (4) |
| Cav1.4wt (s.s.+PD98059) | 1±2 (4) | 3.4±0.8 (4) | 8.4±0.8 (4) | 46±4 (4) | −17±9 (4) | 1.8±0.4 (4) |
| Cav1.4nob2 (s.s) | −4±3 (4) | 2.1±0.3 (4) | 8.7±0.3 (4) | 41±6 (4) | −28±6 (4) | 2.4±0.7 (4) |
| Cav1.4nob2 (s.s.+PD98059) | −5±2 (5) | 2.0±0.9 (5) | 8.4±0.3 (5) | 41±6 (5) | −18±5 (5) | 1.7±0.5 (4) |
s.s. denotes serum starvation for 2 hours; no statistical difference is observed between mouse Cav1.4wt and Cav1.4nob2, or between the constructs when currents were recorded in the absence or presence of 20 µM PD98059 following two hours of serum starvation (p>0.05, one-way ANOVA).