Table 4.

Haplotypes defined by allelic variants (1–7) of four antigens MSP-1-B2:CSP:AMA-1:LSA-1 (respectively), comparing the 1998–99, 2003–05 and 2006 study-years.

Haplotypes MSP-1:CSP:AMA-1:LSA-1	All		1998–99		2003–05		2006
1111	46	36.2%	19	40.4%	6	21.4%	21	42.0%
1112	5	3.9%	4	8.5%	1	3.6%	0	0.0%
1131	1	0.8%	0	0.0%	0	0.0%	1	2.0%
1211	6	4.7%	0	0.0%	5	17.9%	1	2.0%
1212	2	1.6%	0	0.0%	2	7.1%	0	0.0%
2111	3	2.4%	0	0.0%	1	3.6%	2	4.0%
2112	16	12.6%	14	29.8%	1	3.6%	1	2.0%
2121	1	0.8%	1	2.1%	0	0.0%	0	0.0%
2122	3	2.4%	2	4.3%	1	3.6%	0	0.0%
2211	20	15.7%	0	0.0%	4	14.3%	16	32.0%
2212	2	1.6%	1	2.1%	1	3.6%	0	0.0%
2422	1	0.8%	1	2.1%	0	0.0%	0	0.0%
3121	6	4.7%	0	0.0%	4	14.3%	2	4.0%
3211	1	0.8%	0	0.0%	0	0.0%	1	2.0%
3212	1	0.8%	0	0.0%	1	3.6%	0	0.0%
4212	1	0.8%	0	0.0%	0	0.0%	1	2.0%
4231	3	2.4%	0	0.0%	0	0.0%	3	6.0%
5121	1	0.8%	1	2.1%	0	0.0%	0	0.0%
5212	1	0.8%	1	2.1%	0	0.0%	0	0.0%
5323	1	0.8%	0	0.0%	0	0.0%	1	2.0%
5211	1	0.8%	1	2.1%	0	0.0%	0	0.0%
5221	1	0.8%	1	2.1%	0	0.0%	0	0.0%
6111	1	0.8%	0	0.0%	1	3.6%	0	0.0%
7111	1	0.8%	1	2.1%	0	0.0%	0	0.0%
N =	125		47		28		50
Count of haplotypes =		24		12		12		11
Haplotype diversity (Hd) =		0.7932		0.6910		0.8466		0.7543
Hd standard deviation =		0.028		0.055		0.033		0.045