Table 1.

Characteristics of the infants of mothers receiving tramadol and comparator group mothers (n = 75 in each group unless otherwise specified)

Parameter	Tramadol	Control
Sex ratio (M : F)	1.08	0.89
Gestational age (weeks)	38.7 (38.2, 39.2)*	39.3 (39, 39.6)*
Birth weight (kg)	3.4 (3.3–3.5)*	3.4 (3.3–3.5)*
Apgar score 1 min	9 (9, 10)†	9 (9, 10)†
Apgar score 5 min	9 (9, 10)†	9 (9, 10)†
Assessment day post birth	4 (3, 4)†	3 (2, 4)†
Neurologic and Adaptive Capacity Score (total)	36 (33, 38)†‡	37 (33, 40)†‡
Neurologic score component	28 (26, 29)†‡	27 (26, 30)†‡
Adaptive capacity score component	9 (8, 10)†‡	10 (8, 10)†‡

^*mean (95% CI),

^†median (IQR),

^‡n = 67 (data for four infants lost, while four infants were not tested because they were in the Special Care Nursery for prematurity (3) or ventilation (1)). Neurologic and Adaptive Capacity Score range 0–40, composed of neurologic score range 0–30 and adaptive capacity score range 0–10.