Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Observed and predicted AUC increases for CYP3A4 DDIs, where fumic was determined for compounds by equilibrium dialysis (if found to have fumic < 0.1 by ultrafiltration). (A) Chemical inhibitors, (B) Panvera Vmax ISEF, (C) PanVera CLint ISEF, (D) Gentest Vmax ISEF. Solid line represents line of unity, and dashed lines represent ± two-fold boundaries
