Table 1.
rhCYP 1A2 | rhCYP 2C9 | rhCYP 2C19 | rhCYP 2D6 | rhCYP 3A4 | rhCYP control | HL-MIX-101 | |
---|---|---|---|---|---|---|---|
Lot number | 30248A | 29897A | 29896A | 21248 | 29736A | 29870A | 1 |
Specific activity (pmol mg−1) | 105 | 244 | 113 | 118 | 133 | 330 | |
Protein content (mg ml−1) | 10.4 | 4.5 | 9.8 | 8.5 | 8.3 | 10 | 20.4 |
CYP content (pmol ml−1) | 1092 | 1098 | 1107.4 | 1003 | 1103.9 | 6732 | |
Vmax RAF | 0.514 | 1.593 | 0.376 | 0.479 | 0.277 | ||
CLint RAF | 0.319 | 0.900 | 0.292 | 0.138 | 0.146 |