Table 2.
Summary data for rhCYPs purchased from BD Gentest®
| rhCYP 1A2 | rhCYP 2C9 | rhCYP 2C19 | rhCYP 2D6 | rhCYP 3A4 | rhCYP control | HL-MIX-101 | |
|---|---|---|---|---|---|---|---|
| Lot number | 18 682 | 21 | 21 | 22 362 | 24 175 | 13 | 1 |
| Specific activity (pmol mg−1) | 200 | 571 | 217.4 | 129.8 | 244 | 330 | |
| Protein content (mg ml−1) | 5 | 3.5 | 4.6 | 7.7 | 4.1 | 5 | 20.4 |
| CYP content (pmol ml−1) | 1 000 | 2000 | 1000 | 1 000 | 1 000 | 6732 | |
| Vmax RAF* | 0.571 | 1.705 | 0.569 | 1.069 | 0.223 | ||
| CLint RAF | na | na | na | na | na |
*
Values determined using velocity data reported in suppliers data sheets. na, not available.