Table 2.

Comparison of genotype frequencies between the healthy and the heart failure patients

Gene (wt/mut)	Healthy wt/wt	mut/wt	mut/mut	Heart failure wt/wt	mut/wt	mut/mut	Genotype test P value	Allele test P value
ACE (I/D)	18	47	45	5	31	22	0.2800	0.7265
	16.4%	42.7%	40.9%	8.6%	53.5%	37.9%
AGTR1 (A1166C)	48	49	13	23	33	2	0.1205	0.7081†
	43.6%	44.6%	11.8%	39.7%	56.9%	3.5%
AGT (M235T)	51	50	10	16	28	14	0.0074	0.0025
	46.0%	45.1%	9.0%	27.6%	48.3%	24.1%
AGT (T174M)	88	23	0	38	19	1	0.0483	0.0446
	79.3%	20.7%		65.5%	32.8%	1.7%
eNOS (T-786C)	41	53	17	15	34	9	0.3128	0.3498
	36.9%	47.8%	15.3%	25.9%	58.6%	15.5%
eNOS (Glu298Asp)	40	57	14	22	23	12	0.2731	0.6367
	36.0%	51.4%	12.6%	38.6%	40.4%	21.1%
ADRB2 (Gln27Glu)	26	65	20	21	27	10	0.2195	0.2490
	23.4%	58.6%	18.0%	36.2%	46.6%	17.2%
BDKRB2 (+9/−9)	26	59	26	23	23	11	0.0802	0.0670
	23.4%	53.2%	23.4%	40.4%	40.4%	19.3%
CYP11B2 (T-344C)	34	54	23	23	22	12	0.3872	0.4248
	30.6%	48.7%	20.7%	40.4%	38.6%	21.1%
ADD1 (Gly460Trp)	69	38	4	37	21	0	0.4452	0.6707
	62.2%	34.2%	3.6%	63.8%	36.2%

^†Armitage trend test.